ABSTRACT
Oncocytoma of the eyelid is a rare neoplasm. Oncocytoma associated with an ocular surface squamous neoplasm, namely conjunctival intraepithelial neoplasia, is very hard to find in the literature. Herein we report a case of a 53-year-old male who presented with a swelling in the right lower lid over the last 6 years, along with a growth in the conjunctiva of the same eye for the last 2 years and encroaching upon the cornea for the last 4 months. Excision biopsy of the lower lid mass showed histopathological features consistent with oncocytoma. The conjunctival tissue revealed conjunctival intraepithelial neoplasia 3 (severe dysplasia). This case documents a rare synchronous dual ocular neoplasia, a very unlikely coexistence of oncocytoma with conjunctival intraepithelial neoplasia.
Subject(s)
Humans , Male , Middle Aged , Papilloma/pathology , Pterygium , Carcinoma in Situ , Adenoma, Oxyphilic/complications , Eyelid Neoplasms/complicationsABSTRACT
Here, we report an extremely rare case of acquired nasolacrimal duct obstruction caused by oncocytic carcinoma. A 64-year-old man presented to the hospital complaining of epiphora and left-side nasal obstruction. Ophthalmic and otolaryngology examination revealed a left lacrimal duct obstruction caused by a mass in the left nasal cavity and lacrimal drainage system. The mass was removed and confirmed as an oncocytic carcinoma. Nine months after surgery, without adjuvant radiotherapy, a left orbital mass was observed and the patient underwent reoperation. The mass proved to be recurrent oncocytic carcinoma. The patient underwent adjuvant radiotherapy to eradicate any residual tumor and the patient remains tumor-free one year post-radiotherapy.
Subject(s)
Humans , Male , Middle Aged , Adenoma, Oxyphilic/complications , Lacrimal Duct Obstruction/etiology , Nasolacrimal Duct/pathology , Neoplasm Recurrence, Local/complications , Nose Neoplasms/complications , ReoperationABSTRACT
Here, we report an extremely rare case of acquired nasolacrimal duct obstruction caused by oncocytic carcinoma. A 64-year-old man presented to the hospital complaining of epiphora and left-side nasal obstruction. Ophthalmic and otolaryngology examination revealed a left lacrimal duct obstruction caused by a mass in the left nasal cavity and lacrimal drainage system. The mass was removed and confirmed as an oncocytic carcinoma. Nine months after surgery, without adjuvant radiotherapy, a left orbital mass was observed and the patient underwent reoperation. The mass proved to be recurrent oncocytic carcinoma. The patient underwent adjuvant radiotherapy to eradicate any residual tumor and the patient remains tumor-free one year post-radiotherapy.
Subject(s)
Humans , Male , Middle Aged , Adenoma, Oxyphilic/complications , Lacrimal Duct Obstruction/etiology , Nasolacrimal Duct/pathology , Neoplasm Recurrence, Local/complications , Nose Neoplasms/complications , ReoperationABSTRACT
Functioning adrenocortical oncocytomas are extremely rare and most reported patients are 40-60 yr of age. To our knowledge, only 2 cases of functioning adrenocortical oncocytomas have been reported in childhood. We report a case of functioning adrenocortical oncocytoma in a 14-yr-old female child presenting with virilization. She presented with deepening of the voice and excessive hair growth, and elevation of plasma testosterone and dehydroepiandrosterone sulfate. She had an adrenalectomy. The completely resected tumor composed predominantly of oncocytes without atypical mitosis and necrosis. A discussion of this case and a review of the literature on this entity are presented.
Subject(s)
Adolescent , Adult , Female , Humans , Male , Middle Aged , Adenoma, Oxyphilic/complications , Adrenal Cortex Neoplasms/complications , Adrenalectomy , Virilism/etiologyABSTRACT
Adrenocortical oncocytoma is very rare. Less than five functioning types of them are reported and most of the reported cases are incidentally found. We herein report a case of functioning adrenocortical oncocytoma of the left adrenal cortex in a young woman.
Subject(s)
Adenoma, Oxyphilic/complications , Adrenal Cortex Neoplasms/complications , Adult , Cushing Syndrome/etiology , Female , Humans , Immunohistochemistry , Synaptophysin/metabolism , Vimentin/metabolismABSTRACT
Adenomas of the parathyroid gland, the majority of which are of the solitary chief cell type, are the most frequent cause of primary hyperparathyroidism (pHPT). Parathyroid adenomas composed predominantly or exclusively of oxyphil cells are rare and most oxyphil cell adenomas of this organ remain clinically silent. We present here a case of hyperfunctioning oxyphil cell adenoma of the parathyroid gland resulting in pHPT, osteitis fibrosa cystica and simultaneous bilateral fractures upper shafts of femora.
Subject(s)
Adenoma, Oxyphilic/complications , Adult , Female , Humans , Hyperparathyroidism, Primary/etiology , Osteitis Fibrosa Cystica/etiology , Parathyroid Glands/pathology , Parathyroid Neoplasms/complications , ParathyroidectomyABSTRACT
Se presenta un caso de oncocitoma renal desde el punto de vista clínico y anatomopatológico, haciendo énfasis en las características clínicas e histológicas concernientes a diferenciación celular, comportamiento clínico, pronóstico y tratamiento. Los oncocitomas en general son neoplasias raras que suelen presentarse en diferentes órganos como lesiones benignas y/o malignas; sin embargo en el riñón se siguen considerando de naturaleza benigna a pesar de la dificultad en la diferenciación histopatológica con el carcinoma de células renales. Afortunadamente en la actualidad se cuenta con estrategias clínicas y ayudas diagnósticas refinadas que permiten caracterizar la histología de estas neoplasias lo cual permite garantizar un buen pronóstico para el paciente